A pregnancy‐associated nonfamilial case of PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, acne) syndrome

نویسندگان

  • Isao Horiuchi
  • Yuko Fukatsu
  • Junko Ushijima
  • Eishin Nakamura
  • Koki Samajima
  • Kanako Kadowaki
  • Kenjiro Takagi
چکیده

Little is known about the influence of pregnancy on pyogenic sterile arthritis, pyoderma gangrenosum, acne (PAPA) syndrome. We experienced a rare case of pregnancy complicated with PAPA syndrome. The patient had various histories of skin and joint disorders and experienced subarachnoid hemorrhage during pregnancy; however, her skin lesion was unaffected.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Successful combined antibiotic therapy with oral clindamycin and oral rifampicin for pyoderma gangrenosum in patient with PASH syndrome

HS: hidradenitis suppurativa IL: interleukin PAPA: pyoderma gangrenosum with pyogenic sterile arthritis and cystic acne PAPASH: pyoderma gangrenosum with pyogenic sterile arthritis, acne, and hidradenitis suppurativa PASH: pyoderma gangrenosum with cystic acne and hidradenitis suppurativa PG: pyoderma gangrenosum INTRODUCTION Pyoderma gangrenosum (PG) is a neutrophilic dermatitis, the prevalenc...

متن کامل

Pyoderma gangrenosum, acne, and hidradenitis suppurativa (PASH) syndrome with recurrent vasculitis

HS: hidradenitis suppurativa IL: interleukin LCV: leukocytoclastic vasculitis PAPA: pyogenic arthritis, pyoderma gangrenosum, and acne PAPASH: pyogenic arthritis, pyoderma gangrenosum, acne, and hidradenitis suppurativa PASH: pyoderma gangrenosum, acne, and hidradenitis suppurativa PG: pyoderma gangrenosum PsAPASH: psoriatic arthritis, pyoderma gangrenosum, acne, and hidradenitis INTRODUCTION A...

متن کامل

Identification of a homozygous PSTPIP1 mutation in a patient with a PAPA-like syndrome responding to canakinumab treatment.

BACKGROUND Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome (OMIM 604416) is a rare autosomal dominant inherited autoinflammatory syndrome characterized by pyogenic sterile arthritis and less frequently accompanied by pyoderma gangrenosum and acne. It is associated with dominant missense mutations in the proline-serine-threonine phosphatase-interacting protein 1 gene (...

متن کامل

P02-006 - A novel PSTPIP1 mutation in PAPA syndrome

Introduction Pyogenic arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome is an autosomal dominant autoinflammatory disease caused by mutations in the proline-serinethreonine phosphatase-interacting protein 1, PSTPIP1. The produced protein is a cytoskeleton-associated adaptor protein that modulates T-cell activation, cytoskeletal organization and IL-1b release. The only two mutations desc...

متن کامل

Pyoderma Gangrenosum, Acne and Suppurative Hidradenitis Syndrome Treated with Granulocyte and Monocyte Adsorption Apheresis.

Pyoderma gangrenosum, acne and suppurative hidradenitis (PASH) syndrome (1) is described as an autoinflammatory disorder, similar to pyogenic sterile arthritis, pyoderma gangrenosum and acne (PAPA) syndrome, but without joint involvement, thereby satisfying the criteria of a disease entity distinct from infection, allergy and autoimmune disorders (2). A specific genetic mutation underlying PASH...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2016